Points of note : If you have problems locating your license file please switch to Icon View. Points of note: Requires RedNet Control 2. Works with Sierra? NO - VRM Box will appear as an output device and stream audio, however the VRM software will not work. If the serial number starts 'S2' it's a Saffire 6 USB 2.0, if it starts 'SU', it's a Saffire 6 USB 1.1. If you are unsure whether your unit is the USB 1.1 or 2.0 version please check the serial number shown on the bottom of the device. Points of note : If you are using the USB 2.0 version of the Saffire 6, no driver is required. Points of note: If you experience any problems selecting your Scarlett as an input or output device on your Mac, please see this article. Scarlett 6i6, Scarlett 18i8, Scarlett 18i20 ( 1st and 2nd Generation) More information on how to address this can be found here We have encountered an issue where 2nd Generation Scarlett Solo/2i2/2i4 interfaces will appear as a separate Input and Output device in 'Audio MIDI Setup' on the latest build of Sierra (10.12.2). Please follow the steps at the bottom of this article to remove the kext file if your system crashes when connecting a 2nd Generation Scarlett. Works with Sierra? YES - however we are aware of an issue that can cause a kernel panic when using the 2nd Generation 'Low Latency Installer'. Scarlett 2i2, Scarlett 2i4, Scarlett Solo ( 1st and 2nd Generation) Saffire firewire range (Pro 14, Pro 24, Pro 24 DSP, Pro 26, Pro 40, LS 56) Works with Sierra? YES - however there is a known issue with 5k Retina iMacs (model 17,1) when using macOS 10.12.3 and below, please see this article

Please check that all other software/hardware you use to make music is also compatible before updating and never update your operating system during the middle of a time-critical project: Please see below a run-down of Focusrite product compatibility with Apple macOS Sierra as it currently stands.

Mac os 10.12 multiple audio outputs